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Learn about the most prominent differences between the Corona vaccines, Pfizer, Moderna and Johnson



The Corona virus vaccine, developed by Johnson, is waiting for permission to use emergency from the US Food and Drug Administration FDA within the next few hours, and the license will be a third blow after the vaccines Moderna and Pfizer in the plan to confront the Corona virus in the country's arsenal against the virus, according to what was published by Fox News America. .


The difference between the Johnson, Moderna and Pfizer vaccines

While previously authorized vaccines developed by Moderna and Pfizer-Biontec operate on a newer platform using mRNA, or messenger RNA, technology, the Johnson candidate includes a conventionally modified adenovirus vector vaccine with a durable, external protein that encapsulates DNA, lending itself to To a longer storage life.


What is the difference between MRNA vaccines

And conventional vaccines?

While both Pfizer and Moderna vaccines require a two-dose regimen, Johnson's candidate only requires one dose, which helps facilitate logistics.


Late clinical trials showed that the Pfizer vaccine was 95% protective against acute coronavirus disease, while the efficacy was 94.1% for Moderna, and a Johnson candidate had an efficacy of 66.9%. However, the "efficacy" under controlled conditions in clinical trials is not the same. Itself is "efficacy" in imperfect real-world conditions. Results this week showed that the Pfizer vaccine was 94% effective in a global study of nearly 1.2 million people, consistent with the high efficacy reported during clinical trials.


The Johnson candidate vaccine is stable for up to two years at -20 ° C and at least three months at 2 to 8 ° C. Moderna vaccine can last at -20 ° C for six months and from 2 to 8 ° C for 30 days, meanwhile, the FDA has just reduced the allowable shipping and storage temperatures for two weeks for Pfizer vaccine to -25 ° C to -15 ° C in a major shift from extreme cold temperature requirements of -80 ° C and -60 ° C for up to 6 months.


The Pfizer vaccine is licensed for use in people 16 years of age or older, while the Moderna vaccine is approved for those aged 18 and over, such as a candidate for Johnson if the Food and Drug Administration finds it safe and effective. Companies are now evaluating vaccines in younger age groups.

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